Describe the process of excitation contraction coupling

Chapter 21 - Neuromuscular system disorders

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Contraction Physiology | Excitation-Contraction Coupling

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Key babies 'Negentropy', living organization, space-time structure, fallen energy, coherence, coupled cycles, thermodynamics of repeating complexity.

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Excitation-Contraction Coupling

What if a clinical trial would indicate that heart failure patients with a normal maximal oxygen consumption (VO2 max) would show less benefit to aldosteron inhibitors as compared to patients with. InFranco Pacini pointed out the the gravitational energy released when a star collapses would be converted to rotational energy.

"A normal star like the Sun [would] speed up from a rotation period of 27 days to a rotation period of much less than a second when it becomes a neutron star" (Lang and Gingerich ). Words in science are often used in different ways from ordinary English.

Completely different meanings even occur in different branches of physiology, e.g. for the word "accommodation". Contraction Physiology | Excitation-Contraction Coupling. These linked events are referred to as excitation-contraction coupling.

The excitation process begins when the acetylcholine (ACh) is released by a motor neuron at the neuromuscular junction.

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Acetylcholine (ACh) release. Excitation – contraction coupling is the term used to describe the sequence of events that occur after a muscle fiber action potential is generated until the muscle fiber force generates tension.

In the figure shown below the muscle fiber action potential (Na+ in, K+ out) is propagated along the muscle surface and then it spreads downward. Myosin II (also known as conventional myosin) is the myosin type responsible for producing muscle contraction in muscle cells. Myosin II contains two heavy chains, each about amino acids in length, which constitute the head and tail domains.

Each of these heavy chains contains the N-terminal head domain, while the C-terminal tails take on a coiled-coil morphology, holding the two heavy.

Describe the process of excitation contraction coupling
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